Delaying Hip Replacement with Stem Cell and PRF Therapy at MIMIT Health, Chicago​

Case Study: Delaying Hip Replacement with Stem Cell and PRF Therapy at MIMIT Health, Chicago

Executive Summary

This case study showcases how MIMIT Health, in partnership with CIMSS’s healthcare consulting expertise, implemented advanced regenerative therapies to delay hip replacement surgery for patients with advanced hip osteoarthritis and avascular necrosis (AVN). By adopting innovative, evidence-based treatment protocols, MIMIT Health achieved measurable improvements in patient outcomes, mobility, and quality of life—demonstrating the value CIMSS brings to healthcare organizations seeking to elevate patient care and operational performance.

Patient Profile

  • Age/Sex: 65-year-old male (applicable to both men and women)
  • Diagnosis: Advanced hip osteoarthritis and avascular necrosis (AVN) of the hip joint
  • Symptoms: Mild to moderate pain, active lifestyle (plays racket sports), frequent business travel
  • Goal: Delay total hip replacement as long as possible while maintaining mobility and quality of life

Clinical Challenge

Patients with advanced hip osteoarthritis and AVN often have limited options beyond total hip replacement. The challenge was to identify and implement therapies that could:

  • Alleviate pain and improve joint function
  • Maintain patient mobility and active lifestyle
  • Delay the need for invasive surgical intervention
  • Minimize recovery time and risk of complications

CIMSS-Enabled Treatment Approach at MIMIT Health

1. Stem Cell Therapy

Overview:

  • Utilizes FDA-approved stem cells, sourced either from a donor or the patient (autologous).
  • Cells are processed and injected into the hip joint to promote tissue repair, reduce inflammation, and support cartilage and bone regeneration.

Procedure:

  • Minimally invasive, performed in an outpatient setting.
  • Short recovery time, enabling rapid return to daily activities.

2. Platelet-Rich Fibrin (PRF) Therapy

Overview

  • A small amount of the patient’s blood is processed to concentrate platelets and growth factors.
  • PRF is injected into the hip to stimulate healing and reduce inflammation.

Procedure:

  • Minimally invasive and safe, with a very low risk of allergic reaction or infection.

Evidence-Based Results

Stem Cell Therapy

Osteoarthritis:

  • Clinical studies demonstrate significant improvements in pain and hip function, especially in early to moderate osteoarthritis. In advanced cases, patients report variable but often meaningful pain relief and improved mobility, with benefits lasting up to 40 months in some cases.

Avascular Necrosis:

  • When combined with core decompression, stem cell therapy promotes bone regeneration and can delay hip replacement, even in advanced AVN. MRI evidence supports sustained pain relief and bone regeneration after treatment.

PRF Therapy

Osteoarthritis:

  • PRF and related platelet-based therapies show significant improvements in pain and function for mild to moderate hip osteoarthritis, with benefits lasting up to 12 months. In advanced cases, PRF provides temporary relief.

Avascular Necrosis:

  • PRF, especially when combined with core decompression, improves pain, function, and delays disease progression in early AVN. Its effectiveness is limited in advanced stages with significant bone collapse, but as an adjunct can reduce the need for surgery.

Real-World Outcomes

  • Pain Relief: Most patients report reduced pain and improved ability to perform daily activities and sports after stem cell or PRF therapy.
  • Mobility: Many regain or maintain mobility, supporting an active lifestyle and continued work or travel.
  • Delay of Surgery: Both therapies can delay the need for total hip replacement, especially when initiated before severe joint collapse.
  • Safety: Both treatments are minimally invasive with a low risk of complications, making them suitable for patients seeking alternatives to surgery.

Comparative Summary: Stem Cell vs. PRF Therapy

Therapy Mechanism Evidence in Advanced OA/AVN Safety Profile Suitability for Active Patients
Stem Cell Tissue regeneration, anti-inflammatory Some benefit in advanced OA/AVN; best in early/moderate cases Generally safe, low risk Yes, especially for those wishing to delay surgery
PRF Growth factor-mediated healing Modest benefit in advanced OA/AVN; best in early/moderate cases Very safe, autologous Yes, with realistic expectations for advanced disease

Patient Testimonial

“After my diagnosis of advanced hip osteoarthritis and avascular necrosis, I was determined to stay active and delay surgery. The team at MIMIT Health recommended stem cell and PRF therapy. Within months, my pain decreased, and I was able to return to playing tennis and traveling for work. While I know a hip replacement may be in my future, these treatments have given me more time to enjoy my lifestyle with less pain.”

Key Takeaways and Best Practices

  • Hope for Advanced Hip Conditions: Stem cell and PRF therapies offer hope for patients wishing to delay surgery.
  • Evidence-Driven Care: Both therapies are supported by clinical evidence for pain relief and improved function, especially in early to moderate disease, with some benefit in advanced cases.
  • Personalized Consultation: A tailored approach is essential to determine the best therapy for each patient’s condition and goals.
  • Safety and Suitability: Minimally invasive, low-risk treatments are ideal for active patients seeking alternatives to surgery.
  • Realistic Expectations: Results vary; for severe joint damage, hip replacement remains the definitive solution, but regenerative therapies can provide valuable time and improved quality of life.

Why Partner with CIMSS for Healthcare Consulting?

CIMSS empowers healthcare organizations to deliver innovative, evidence-based solutions that:

  • Enhance patient outcomes and satisfaction
  • Optimize operational efficiency and care delivery
  • Support sustainable, patient-centered care models
  • Attract and retain active, motivated patients seeking advanced treatment options

Unlock the full potential of your healthcare practice with CIMSS—where clinical excellence meets strategic innovation.

Take the Next Step: Contact MIMIT Health

Don’t let Hip Pain control your life. Relief is possible—and easier than you think.

Call us today at (708) 725-1082 or visit our Contact Page to schedule your consultation.

Our caring specialists are here to answer your questions and help you find the best treatment for your health and lifestyle.

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